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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3753acd7d2fdc5b80f1c8a303e3e3f81e331322da61a9ff5f70ba955eb30d4' 
  AND token = '6cMPAtV3QTNF8IUe/m2AH7gzbvn/qYjYGhEXjffAj7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}