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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535efe936b837271ea26a929e2532f68a33523b121bd85582c21f3d3bd20445f' 
  AND token = 'kNGfmw1Bj+4fJMm0UDlWREe7T1tjmased6Ltm5XEnYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}