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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '012f7baf823d8dfe05322291f85e17fdd863cd71af8d3711b6bf484cb1ef8378' 
  AND token = '8IJw3+5cim+X3VzMZ1Z2/3FBkS4vKGFnC/Gb7oMj8s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}