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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '976a70facdbe8b9430d0f88a4b227daa0997c8ce2edacc737aa23e7a0f52a694' 
  AND token = 'XrfDm+iQ6faqOPKkgC0F48wnuRQuhkB2BvwKgVjL+Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}