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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e20a0b01d18feaa62bd5293e2e024dc459a0cd1c6e3cd7b346f0792a3f53f0' 
  AND token = 'IypGeTG4d2mKiAqJMXDqFutp2Pha1OCkbNL5omDF9+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}