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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d43802c109b4adc835fc1b4e9c6e59ea2ae805578fb4ef382bf923d254aaf3c' 
  AND token = 'vyKnPOs1zWPyM/OVnRJ7bkxnmfg+WLckQFbAN0cmWl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}