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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2691c9287b0823ca4f1bdbbf71df08a2c631875ff58cdfbabcc337608e7fda3' 
  AND token = 'lR3bxqTtOAjRImfVIOhJ6Uav4ZLR9WkoqSqMORgP1Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}