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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca29160bd4d8bbbe3e0156564e4f104303ce0a2aa25e6bbe98d0616a379b6be' 
  AND token = 'gG1vGGzIUY+8SrrJ4ggIlA1S8hcTZiYdY9u4kMBs0Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}