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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645233ac8a31b7417bf1ec0afe951bf6bff9c245f477b3e29f9647d0bbad3a36' 
  AND token = 'EoQ4BlUIik3aGyq0T/LgQ+WCgc+mFl9+lTaD/G5/0Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}