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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eef0cebc5e5a424d022fc1b453cd4df07fe67a0f9a684d9adade73f95cca199' 
  AND token = 'Qf18GgAofvg0TDSh/DtkObKaEXlmGS4c/H525Rb6KrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}