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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d399061e5bd5f6dd03e04576f1c44e4ab28264b74c94147e3c8d61e48a2f75' 
  AND token = 'IHomqs+9+bY14aoBee5fXTfxJNQfRQaFfTYiR3ueXc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}