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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87c9b11e53ba7732b80f46e4417f827ce8aafeac7eadeb3574f974cda679dd9f' 
  AND token = 'EVHD2B4lFzbbyYT8gz6QuC5v4mLflOysa3TqcT+LP1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}