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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54e8410ff24cbc3f66d272e3e36cfd7c800d27722cb176ed922f712693dbd40' 
  AND token = 'uVjJd/t8nuecNlh8Cwz+1htfIcwb75gL+2fbAjrznag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}