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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f412bbbefe9db533e00fd25b8266ded6160aa9cc0b24e01b546fe34a217af741' 
  AND token = 'X60fUGTQSK7E13JTiC6DdlXR4tTorMxrOCgeDdM1nGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}