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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed34012d4df21f12f1f75a96e40140fb19580ed2843299bfd52abf89d711ebe' 
  AND token = 'hsQ448cuBD4kr1Csh4vcxiZ0LgeZdxqgUkA3babYCvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}