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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10e3b5914a4db5935e1b1d80f2cd7412f4f98b18f42befaaeab18fb892427cc' 
  AND token = '5MlNUxH0Q2adN0a8Ferj/LOJCcpl/02dLdfCIe+ZDcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}