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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85476a5c160efa4e711679ccd9f18cec81fe0c89d05a4200ca341a4389ed4876' 
  AND token = 'P8wyY1E0DU+zG/EmVEY2YKMXJO8KyiGMjXJ+iGwMGno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}