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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4f3c5096729ed9b881f577a3b248132cee639b182ca132a6c4555801928a02' 
  AND token = 'zZgEwb0UCQ7b0e2AxhyCuwwf9gCL+5Ye5gON1wl0oSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}