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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14bb19a9ceee02fe19ed5acdd48f70176dd709f83356ee519477d6e43143376' 
  AND token = '+XADlHSV7g2CnU2Q6TLA8gCxql4NGPGu4FWQy9meb/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}