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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5043b6a865e73dac5e67be9780a5bbd45fc7b1ca237669915c043eb4a5e2d8e8' 
  AND token = 'si4h3X6ll+11Dwad+Z5DYY9cwKPc/vUyq0/IuCj2hWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}