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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eee09ca3de7566a5003f9f1c1963db545158c916611a25f96cd6885eed5f976' 
  AND token = '7GVxlWNbKAqkMTU4vcuu0JZADBkNWrA9Ba5ZdP5L2Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}