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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58da6a9e3eab2567c83832c334225a6be6065f449e14df7c969c5ae157c41b2d' 
  AND token = 'wtAB1/buz/DqlM2D129Rql3rWdiq8lgiY5THRw/cXj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}