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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13253864ba5790e36be61b4e8226bcbfa4f478afc0e1ae7dde7d91d0cc989688' 
  AND token = '+dDVuMdwKF60yB5NB/W8t8+FrUE8MrYcjeEXG7PzPcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}