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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab0b91e6813be704d649a9212a4bc0706da514e38cedfdff41fb798a0a257756' 
  AND token = '1CsDsm1sW2qR8zA6n0RH1GAG9+9RwQoYErJKja6BQ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}