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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e333b68d126b15d3688c521740c21903c00455338a36e1de1b986168f5dfa942' 
  AND token = 'Me+hg1tXVy6LQS+6FKTySi6sayfAJqw/giK49ev8Zl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}