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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7ce3344f62465dc9689a7fe9d41ca5c57ff553d43b88fd3a3b582e729e7aae6' 
  AND token = 'tlsCAOgw5l+U3jhKkedtaK9Wt5CUo8bAxLS8ZSmExB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}