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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cbeefd6d772a00c2c0f41499227a7e111ac3db54fedf2fca04b962579a58d10' 
  AND token = '7V9PY9X+/2bpj9xszocao7XhubkFEwXreR9WUeMZqeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}