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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e8f9eecd6a82c2456c819959f3b89ea9a62fd72c1d806df4ae537a246f67db' 
  AND token = 'Y53XSIszHMQ3yIH33OfvFUJGnwg5xbrw6SHZ0uv/c8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}