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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25100e8227899c9ce2667d3b4c572f506497ca70c178ac85d3c367ff9b06023d' 
  AND token = 'ie70uwsR/BnI5ocvUsn3nbmLMGufv1Ij/aNSb1B95R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}