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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12c2a6e50938a2aeb067ae00afae68cd3a77db5c00be1458a7decb4ef6fcca1' 
  AND token = 'ZMyHUjdeZZ9MWHVcJCSc7LfV+PzjkQjoGUnpxRVrrew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}