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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '716290f9f0644b5489210fa27d5cdb505d912848bd5959fdb29aaf26ea67f9db' 
  AND token = 'vOF6ur+u42PByM+sYpnUfH+Bm7Kh3cVemumxOM4iQqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}