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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c22851fca94b74ab6cd9bb93dd756e6c9b717ef2fddd1346ed9ed2e5e04665' 
  AND token = 'JVZewE+94pnEJqb77gHHI7wB+y/1rzjstdXziZM/Q1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}