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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a5348f4d2f076759b6d4ca4bb8fd72ca4ba781f1228fba35341b9434bdd994' 
  AND token = 'vb0RnYjbHal/Tb2WvJlFf6UygJD4LvhjlkgtqXFifEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}