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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e04066a9e9391a96acfe1aa979e9049fc41d41130bf73bab173820c4f2e73a' 
  AND token = '6UI049QwFpSZOlEzx2RezHBkPlYpERDJMmWSuT6abWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}