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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852b3fe7143b1690f7e2008ae486741aaa622c40915e2f6ed6c056c8b762437a' 
  AND token = 'eN/e6mc2cylSxY8J1kQ6fUNF56wvVLikTyvtkV73Vl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}