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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6d896698963d99a075f0bd57f6d5f8b0694d2b8d3ee8f76483100023005eb58' 
  AND token = 'e4DdaqXZ+8kCXQrfZTLUZ2S2t3+HQhbppyDSxUFz5pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}