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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd5da4200b6c674d2389a64f76812aeb206ecafa93de00036cd867bf3a7aec54' 
  AND token = '03I9M1Y1GbL+rBwIXp2uIfsHcFeUj0IQgfTOmOaOwLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}