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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '079e13d4334eaf6f4db2ca56733db40e21b9917084af9c1400282b8aab7de9ec' 
  AND token = 'JUx9/PtI2Hqd98ij/lDX+n2+2tzBiY5jRiDWv4u6vDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}