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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d072cd1521a1883239f9d8d5e3bcc5e88f1446b0be44d524f231e955b876de4' 
  AND token = 'oYyZZsp2FoM0mY5itfi73x1DFoaEg6boUzCyJ57fVOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}