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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e472226b96a21f94c9124f1b8d4c74a834ce3afbfe8f6be2998dc1efbc501b' 
  AND token = 'If5EUH9d3bh9ul3sLUTybxdLugag9FG+BmJiciFW9L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}