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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a0c33c7e136e6dc78039ab1030c04ef8cc451bf949d1dccff109b99b8dd3043' 
  AND token = 'udNoBmMqmAQvsjRDyjL2Sw9cRgYgWudv7LQFSLiqk6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}