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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8eb75a4aa80292068cc48f0e70093c8236b745bc68e59ed4dd4bbd6030b480' 
  AND token = 'ugXajG/Dk0rr8vVo/Bp4SNh642eWTxCsoijpgN8unBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}