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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '126dfa2cde30464d9c817985baa6b8eb34fd31fbab35392d689d81b175b3824d' 
  AND token = 'IiNxSGE+p8Ff7G4XRZMDeftx3NiLB1Wo35heEykAgUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}