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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7447e98a9c31a0279cfd94f8d9090fb48a874b405d3850f76e308263bd0baf88' 
  AND token = '1we/Jgg48OLXBpxzQvlT7pHoD+LX2imBWxf6EaqHI44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}