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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104ccfeba7c3bd8764e0231cbf7126e9ad6056957d1b8181a4e7d65b59bb1d60' 
  AND token = 'aUtCNCkQhsEi7bFkz4+UQqHhz+8VlIfihfKUGmo7xwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}