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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e7d85caf1400b83a85a196cf2c74b763356605cd67d9db2d23084521cc8fae' 
  AND token = '+AaF8x5S75ddYSQ9MA27uOAgWxu/dyi0ERWtOYRBdX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}