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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f3cde89b34adacf7b1b38ad882143da325c07b6a74ae755a4f1784a549271c' 
  AND token = '6QA6/2f7HayJURC8yLYoX6kZJGVTwN4rnCanMIhJSZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}