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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7939b01def9090d02faee02d5be415dbd8fd28f6e7709bc47dda6cd03bdd1dc1' 
  AND token = '3CxxNs+5kWhDzoEo0FYBq3LqQ9YkCIOXW853LocTSMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}