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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e6e995555fb19e1d9c6445fd49160f4ff85eb88d551b041266f7bb0a81d384' 
  AND token = 'Vc55/iolS7rAjpOJhNfq+Gs1hpLUxW1EpngMMOPoi74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}