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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c87565ce7366d434ed98276e835cfa9e12f215e3b230d157b18408edb64cece' 
  AND token = 'kccVyoNvFNaJxUqcyG99c9ckh5BlRHA9Wb2y7XPbPyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}